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主观认知下降生化诊断标志物的研究进展
Research progress of biochemical diagnostic markers of subjective cognitive decline
- 重庆医科大学学报 2021年46卷第11期 页码：1348-1351
- 作者机构：
上海交通大学附属第六人民医院老年病科，上海 200233
- 作者简介：
[ "陈奕馨，Email：chenyixin1006@163.com，研究方向：老年医学。" ]
苗雅，副主任医师，医学博士，硕导。上海医学会老年医学专科分会青年委员会副主任委员、中华医学会老年医学分会第十届委员会青年委员、上海市医学会老年医学专科分会第十届委员会神经精神学组委员、《实用老年医学》青年编委会编委、中国老年医学学会认知障碍分会第一届委员会神经心理量表评估学术工作委员会委员、中国女医师协会第一届老年医学专业委员会委员；承担国家自然科学基金、上海市科委自然科学基金及校局级课题多项，在国内外相关期刊发表论文20余篇，其中SCI收录10余篇。Email：nning-my@163.com。
- 基金信息：上海市自然科学基金资助项目(19ZR1438800)
DOI：10.13406/j.cnki.cyxb.002924
中图分类号： R749.16纸质出版日期：2021-11-28，
收稿日期：2021-07-06，
扫 描 看 全 文
陈奕馨, 程丽珍, 苗雅. 主观认知下降生化诊断标志物的研究进展[J]. 重庆医科大学学报, 2021,46(11):1348-1351.
Yixin Chen, Lizhen Cheng, Ya Miao. Research progress of biochemical diagnostic markers of subjective cognitive decline[J]. Journal of Shanxi Agricultural Sciences, 2021,46(11):1348-1351.
陈奕馨, 程丽珍, 苗雅. 主观认知下降生化诊断标志物的研究进展[J]. 重庆医科大学学报, 2021,46(11):1348-1351. DOI： 10.13406/j.cnki.cyxb.002924.
Yixin Chen, Lizhen Cheng, Ya Miao. Research progress of biochemical diagnostic markers of subjective cognitive decline[J]. Journal of Shanxi Agricultural Sciences, 2021,46(11):1348-1351. DOI： 10.13406/j.cnki.cyxb.002924.
摘要
阿尔茨海默病（Alzheimer's disease，AD）是痴呆的主要病因之一，主观认知下降（subjective cognitive decline，SCD）被认为是AD的临床前期，早期诊断SCD对AD的防治具有重大意义。在SCD的各种诊断方法中，生化诊断手段是一种较为简单、成本低廉、创伤小的诊断方式。将生化诊断方法与神经心理评估方式相结合，在SCD的诊断中具有较好的前景。本文就SCD的脑脊液、血浆、尿液等生化检测方法的研究进行综述。
Abstract
Alzheimer's disease (AD) is one of the main causes of dementia
and subjective cognitive decline (SCD) is considered as the pre-clinical stage of AD. Early diagnosis of SCD is of great significance to the prevention and treatment of AD. Among various diagnostic methods of SCD
biochemical diagnosis is one relatively simple
low cost and less invasive. The combination of biochemical diagnosis and neuropsychological assessment has a good prospect in the diagnosis of SCD. Therefore
this paper has reviewed the research on cerebrospinal fluid
plasma
urine and other biochemical detection methods of SCD.
关键词
主观认知下降阿尔茨海默病生化诊断标志物
Keywords
subjective cognitive declineAlzheimer's diseasebiochemical diagnostic markers
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