Gut microbiota interacts with the central neural system. Gut microbiota can regulate neural system

endocrine system

and immune system

etc.

thus leading to the progress of neurodegenerative diseases. This paper reviews the research history of the gut microbiota

and focuses on its current progress in neurodegenerative diseases including Alzheimer's disease

Parkinson disease and amyotrophic lateral sclerosis. Accumulating evidence indicates that the gut microbial homeostasis may be destroyed in neurodegenerative diseases. Therefore

the maintenance of normal gut microbial homeostasis

such as by antibiotic and probiotic therapy and fecal transplantation

will provide new ways and ideas for the prevention and treatment of these kind of diseases.