Objective: To investigate the pathogenesis

clinical features

and surgical treatment of intravenous leiomyomatosis with intracardiac extension

and to improve the understanding of this disease. Methods: We retrospectively analyzed the clinical data

diagnosis and treatment of 3 patients with intravenous leiomyomatosis with intracardiac extension in The First Hospital of Lanzhou University

and reviewed relevant literature. Results: All the 3 patients were successfully treated with surgery. Among them

2 patients underwent thoracoabdominal incision with one-stop surgery of "uterine

accessory

pelvic mass resection and removal of intracardiac and inferior vena cava tumors". Another patient's surgery was performed in two phases. During the first phase

"right atrial mass resection+tricuspid valvuloplasty" was performed firstly. After 1 week

we performed a second surgery "full hysterectomy+bilateral adnexectomy+removal of inferior vena cava tumor+right ureteral stent implantation". All 3 patients were successfully operated and recovered and discharged after the surgery. Conclusion: Intravenous leiomyomatosis with intracardiac extension is rarely seen in clinic. Thorough resection of the tumor is the key to the treatment of this disease. The surgery requires multiple disciplines to be combined

which can be completed in one-phase one-stop

or can be completed in stages by stages. Two kinds of surgical methods both can achieve satisfactory therapeutic effect in clinic.