Objective: To explore the clinical application value of endoscopic nasobiliary drainage (ENBD) in the treatment of left hepatolithiasis complicated with choledocholithiasis under simultaneous triscopy (laparoscopy

choledochoscopy and duodenoscopy). Methods: A total of 49 patients with left hepatolithiasis complicated with choledocholithiasis with or without cholecystolithiasis treated in the Department of Hepatopancreatobiliary Surgery of The Second People’s Hospital of Chengdu from January 2014 to July 2018 were analyzed retrospectively. All patients underwent laparoscopic regular hepatic lobectomy and laparoscopic choledocholithotomy. Among them

22 cases were treated with ENBD (observation group)

and 27 cases were treated with T-tube drainage (control group). The clinical effects of these two ways were comparatively analyzed. The observation indicators were perioperative period and the follow-up situations. The follow-up was made by telephone. SPSS 20.0 statistical software was used for the data analysis. Results: The postoperative exhaust time in the observation group was earlier than that in the control group

which was (57.4±13.4) h and (67.9±12.7) h

respectively

with statistical significance (t=-2.818

t=0.007

all P<0.05). The postoperative tube-taking time of the observation group was (4-12) d

which was significantly shorter than that of the control group (75-95) d

with statistical significance (Z=6.022

Z=0.000

all P<0.05). Conclusion: In view of the limited case study in our hospital

ENBD carried out in patients with left intrahepatic hepatolithiasis complicated with choledocholithiasis has the advantages of accelerating the recovery time of gastrointestinal function and shortening the tube-taking time

indicating that it’s a safe and effective surgical method.