Objective: To analyze the current situation of birth defects in Sichuan Province in recent years and put forward feasible preventive reference measures

so as to further reduce the level of birth defects in Sichuan Province and improve the quality of the born population. Methods: The hospital monitoring data of birth defects in the whole province from 2010 to 2018 were analyzed and related database was established. Epidata 3.1 was used to input the data and SPSS 22.0 software was used to conduct statistics and analysis. Results: From 2010 to 2018

the overall incidence of birth defects in the province was 150.51 per 10 000

a decrease of 20.70 percent in 2018 when compared with 2010.Some serious birth defects

such as neural tube defects

had a significant downward trend. Congenital heart disease had been becoming the first order deformity for six years in a row. Conclusion: The prevention and treatment of birth defects in ethnic minority areas and rural areas should be well carried out

the construction of the network system of birth defects should be strengthened

the prenatal diagnosis level of the whole province should be improved

and the implementation of birth defects policy and investment should be the focus of the prevention and treatment of birth defects in the whole province.