Glaucoma

as the first irreversible blinding disease worldwide

severely impairs people’s vision health

but with unclear pathogenic mechanism. A large quantity of researches have demonstrated the close relation between myopia and glaucoma

especially open-angle glaucoma. Structures of high myopic eyes are mechanically stretched in axial elongation and lead to various pathophysiologic changes associated with glaucomatous damages

so as to cause the increased onset risk for glaucoma. This study retrospectively analyzed papers published in the past 10 years at home and abroad and reviewed structural and functional changes in myopic eyes and their relationship with the etiology of primary glaucoma.