Mao Lei, Yuan Yuqing, Cheng Chongjie, et al. Correlation between the early coagulation function and delayed cerebral ischemia after aSAH[J]. Journal of Chongqing Medical University, 2017,42(12):1631-1634.
Mao Lei, Yuan Yuqing, Cheng Chongjie, et al. Correlation between the early coagulation function and delayed cerebral ischemia after aSAH[J]. Journal of Chongqing Medical University, 2017,42(12):1631-1634. DOI: 10.13406/j.cnki.cyxb.001438.
Objective:To investigate the correlation between the parameter of early coagulation function and the incidence of delayed cerebral ischemia after subarachnoid hemorrhage and to provide basis of early prediction and intervention for delayed cerebral ischemia in clinical treatment.Methods:The coagulation and TEG of 77 patients with aSAH within 24 hours from onset was analyzed retrospectively and 22 cases of unruptured aneurysms(UIA)were collected as matched group.aSAH patients were divided into the DCI group(38 cases)and No-DCI group(39 cases)to compare the clinical data
coagulogram and parameter of TEG.The multi-factor logistic regression analysis was adopted to determine the risk factors.Results:Compared with those of the No-DCI group
the values of DD
FDP
Fib
α and MA in DCI group were significantly higher(P=0.000
0.000
0.000
0.043
0.042)
while values of R and K were lower(P=0.002
0.036).The result of multiple-factor analysis shows that the parameter of D-D and K were the independent risk factors.Conclusion:The parameter of D-D
FDP
Fib
α angle
MA is significantly increased
while the parameter of R and K is significantly decreased in aSAH.D-D and K are independent risk factors of DCI.Therefore
early monitoring of coagulation function can help predict the occurrence of DCI