Objective:To compare the efficacy of finger pressing method and cotton ball with adhesive plaster pressing method after removal of the needle in CT enhancement scan. Methods:Totally 1 465 patients with clear consciousness

correct expression

willingness to cooperate and normal coagulation function received the CT enhancement scan in our hospital in December 2016

and all were

punctured for the first time without leakage of the contrast agent. The patients were randomly allocated into experimental group（n=752）and control group（n=713）. Patients received a cotton ball with adhesive plaster pressing method in experimental group and finger pressing method for local compression after removal of the needle in CT enhancement scan. Chi-square test was used to exam-ine the difference of patient satisfaction

pain degree

and bleeding associated complications. Results:Patients’ age

communication ability

cooperative degree

coagulation function

and difficulty degree of vascular puncture were comparable between the two groups.Compared with finger pressing method

cotton ball with adhesive plaster pressing method was associated with improved satisfaction rate（97.03% vs. 90.87

P=0.000）and decreased risks of complications

including incidence of moderate and above pain（8.37% vs.18.65%

χ

2

=33.348

P=0.000）

incidence of needle eye bleeding（0.93% vs. 2.67%

χ

2

=6.312

P=0.012）

incidence of hematoma（0.53% vs. 1.96%

χ

2

=6.181

P=0.013）

and incidence of subcutaneous hemorrhage（0.80% vs. 2.52%

χ

2

=6.772

P=0.009）. Conclusion:The cotton ball pressure press method is more safe

effective

easy and better prevent compression complications and improve patient satisfaction than finger press method. So

it should be promoted to clinical applications.