Objective:To describe the status quo of demoralization among cancer patients

and to explore its influencing factors. Methods:A cross-sectional survey was conducted. The Demoralization Scale-Mandarin Version（DS-MV）

the Medical Coping Modes Questionnaire

Patient Health Questionnaire-9（PHQ-9）

Mc Gill Quality of Life Questionnaire were delivered to 523 cancer patients. Results:The overall demoralization score for cancer patients was 33.53±15.09. The single factor analysis showed that there were statistical significant differences among scores of cancer patients with different demoralization status

occupations

education

family income

payment methods

habitats and disease stages（P<0.05）. The Pearson correlation analysis showed that the demoralization of cancer patients was positively correlated with depression

resignation coping style

psychological dimension of quality of life（r=0.623

0.589

0.572

P<0.05）

but negative correlated with the overall quality of life

the individual existence dimension and the social support dimension of quality of life（r=-0.379

-0.572

-0.453

P<0.05）. Multiple linear regression results showed that factors influencing demoralization including occupation

education

depression

resignation coping style

avoidance coping style

psychological and individual existence dimension of quality of life（β =0.596

1.373

0.744

1.265

-0.512

1.083

-1.411

P <0.05）. Conclusion:Cancer patients have high demoralization. Occupation

education

depression

avoidance coping style

resignation coping style

psychological and individual existence dimension of quality of life are important influencing factors.