早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究

宋延波; 甘露; 陈晓品; 张涛; 童立纺

doi:10.13406/j.cnki.cyxb.001351

您当前的位置：

首页 >

文章列表页 >

早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究

肿瘤相关研究 | 更新时间：2024-01-17

- 早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究
- Dosimetric comparison of electronic tissue compensation and three dimensional radiotherapy in early-stage breast cancer patients after breast-conserving surgery
- 重庆医科大学学报 2017年42卷第11期页码：1417-1421
- 作者机构：
  
  重庆医科大学附属第一医院肿瘤科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001351
  中图分类号： R737.9
- 纸质出版日期：2017，
扫描看全文
宋延波, 甘露, 陈晓品, 等. 早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究[J]. 重庆医科大学学报, 2017,42(11):1417-1421.

Song Yanbo, Gan Lu, Chen Xiaopin, et al. Dosimetric comparison of electronic tissue compensation and three dimensional radiotherapy in early-stage breast cancer patients after breast-conserving surgery[J]. Journal of Chongqing Medical University, 2017,42(11):1417-1421.
宋延波, 甘露, 陈晓品, 等. 早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究[J]. 重庆医科大学学报, 2017,42(11):1417-1421. DOI： 10.13406/j.cnki.cyxb.001351.

Song Yanbo, Gan Lu, Chen Xiaopin, et al. Dosimetric comparison of electronic tissue compensation and three dimensional radiotherapy in early-stage breast cancer patients after breast-conserving surgery[J]. Journal of Chongqing Medical University, 2017,42(11):1417-1421. DOI： 10.13406/j.cnki.cyxb.001351.

摘要

目的:比较早期乳腺癌保乳术后采用三维适形放射治疗(three-dimensional conformal radiotherapy

3DCRT)和电子组织补偿(electronic tissuecompensation

eComp)两种不同放疗方案的剂量学差异。方法:60例早期乳腺癌保乳术后放疗患者

在专用软件上分别设计3DCRT和eComp 2种方案并比较设计方案所耗费时间、辐射剂量机器监测单位(monitor unit

MU)、肿瘤靶区剂量覆盖和正常组织器官受照射剂量等参数之间的差异。结果:设计放疗方案所耗费时间

eComp约比3DCRT多10 min

差异有统计学意义(P=0.000)。3DCRT和eComp的平均MU分别为(300±12)、(302±11)MU(P=0.059)。2种方案都能满足肿瘤靶区的剂量覆盖标准;采用eComp方案

肺、心脏和皮肤剂量更低(P<0.05)。结论:在保证肿瘤靶区得到足量照射的前提下

eComp技术可以降低肺、心脏和皮肤的受照射剂量。

Abstract

Objective:To perform a dosimetric comparison of electronic tissue compensation（eComp）and three-dimensional radiotherapy（3 DCRT）in whole breast irradiation for early-stage breast cancer patients. Methods:Sixty patients who were treated at our institution were selected for this study. 3 DCRT and eComp planning techniques were used to generate treatment plans for all patients

respectively. The radiotherapy planning effectiveness including process timing

monitor unit

target volume coverage and dosimetric difference of critical organs doses between 3 DCRT and eComp were compared. Results:On the average

eComp treatment planning process was about 10 minutes longer than 3 DCRT plans. The mean numbers of monitor units required to deliver the 3 DCRT and eComp were（300±12）MUs and（302±11）MUs

respectively（P=0.059）. The PTV coverage between 3 DCRT and eComp plans was similar. eComp plans delivered lower doses to lung

heart and skin in comparison to their corresponding 3 DCRT plans. Conclusion:eComp technique leads to improved dose of lung

heart and skin without compromising of the targets dose coverage.

关键词

乳腺癌放射治疗剂量学比较

Keywords

breast cancerradiotherapydosimetric comparison

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

基于机器学习的病理组学特征可预测乳腺癌患者对新辅助化疗的反应

环状RNA hsa_circ_0002185对乳腺癌细胞瘤细胞活力和侵袭能力的影响及其作用机制

乳腺癌相关抗原ROR1 H-2Kd限制性CTL表位预测及初步鉴定

乳腺癌根治术后全X线照射胸壁及锁骨上区平卧位和胸骨水平位的肺剂量学比较

172例乳腺癌输液港静脉血栓相关因素分析