Objective:To explore correlation between chronic inflammation and coronary atherosclerosis(CAS)according to pathological method. Methods:Medical records and autopsy data of patients with CAS and/or chronic inflammatory diseases were analyzed retrospectively. Results:There were 216 patients with CAS accompanied with mild chronic inflammatory diseases. One hundred and fifty-nine patients were male and 57 patients were female. Left anterior descending branch was the most vulnerable part to atherosclerosis and stenosis. There were 196 patients with chronic bronchitis(CB)in CAS patients. There was a positive correlation between CB and CAS(rs=0.404

P=0.000)

and chronic bronchitis was one of the risk factors of CAS(OR =4.852

95% CI =2.898 to 8.124

P=0.000)

whereas other chronic inflammation

such as chronic pyelonephritis

chronic gastroenteritis

chronic esophagitis

chronic lymphocytic thyroiditis and chronic cervicitis and CAS had no significant correlation with CAS(P >0.05). Conclusion:CB is one of the risk factors for CAS. It is important to treat CB so as to decrease the incidence and mortality of coronary heart disease.