Multiple sclerosis（MS）is an idiopathic inflammatory demyelinating disease in common central nervous system. It demonstrates a chronic remission relapse course;its etiology is unknown so far and there is no cure for it. It is one of the main causes of non traumatic disability in young adults

which is a serious burden to the family and society. There is increasing evidence that mitochondrial dysfunction plays a role in the development of MS. In this paper

we review the correlation between mitochondrial dysfunction and MS.