Objective:To investigate the clinical features of extremely low birth weight infants(ELBWI)in our hospital for nearly twenty years;to analyze the risk factors of mortality and to evaluate long-term outcomes. Methods:Prenatal data of 87 ELBWI were collected from 117 newborn cases who admitted with weightless than 1 000 g and equal to 1 000 g in Children’s Hospital of Chongqing Medical University between July 1994 and December 2013. When connected we measure both growth and mental development. Results:Of 87 ELBWI

21.84% survived

6.90% died at hospital and 71.26% abandoned treatment. Average gestational age(t=2.4

P=0.016)

and proportions of test tube baby(χ2=5.018

P=0.025)

antenatal steriods(χ2=8.809

P=0.012)and maternal pregnancy induced hypertension(χ2=7.513

P=0.031)

enteral nutrition(χ2=15.046

P=0.000)

transfusion of albumin(χ2=4.629

P=0.006)

red blood cell(χ2=19.97

P=0.000)and immunoglobulin(χ2=4.660

P=0.031)were higher in better prognosis group than in poor prognosis group

while usage of mechanical ventilation was higher in poor prognosis group(χ2=15.155

P=0.000). Composition of complication in two groups was different. Telephone follow-up was conducted for 11 cases out of 19 cases

in-patient follow-up for 6 cases out of 11 cases. The oldest was 11.4 years and the youngest was 1.3 years. One case of growth restriction and two cases of development restriction were observed.Conclusion:With the improvement of survival rate of ELBW

focus should be paid to the longitudinal follow-up of growth and development.