Chen Liu, Liang Ziwen. Application of metformin in the treatment of type 1 diabetes[J]. Journal of Chongqing Medical University, 2016,41(11):1098-1100.
Chen Liu, Liang Ziwen. Application of metformin in the treatment of type 1 diabetes[J]. Journal of Chongqing Medical University, 2016,41(11):1098-1100. DOI: 10.13406/j.cnki.cyxb.001045.
Insulin replacement is the basis for the treatment of type 1 diabetes
but long-term clinical usage of insulin also brings many problems
particularly weight gain. More and more clinical studies of metformin in type 1 diabetes as an adjunct treatment showed that metformin did reduce the amount of insulin and weight gain
but whether there is cardiovascular benefits needed more clinical researches.