Objective:To study the characteristics of serum lipids of patients with pulmonary tuberculosis and bacterial pneumonia and to explore its correlation with sputum smear results. Methods:Objects were from the Second People’s Hospital in Weifang city

Shandong province. There were there groups:460 pulmonary tuberculosis patients treated in hospital（single-tuberculosis group）

315 pulmonary tuberculosis & bacterial pneumonia patients treated in hospital（tuberculosis & pneumonia group）

and 434 healthy check-ups in the same period（healthy controls）. Objects’ fasting blood was drawn in the morning

then centrifuged and the concentration of serum total cholesterol（TC）

triglyceride（TG）

high density lipoprotein cholesterol（HDL-C）

low density lipoprotein cholesterol（LDL-C）

lipoprotein（a）（Lp（a））

apoprotein A1（Apo A1）

and apoprotein B（Apo B） was tested. TC and TG were tested by enzymic method

HDL-C and LDL-C were tested by selective-covered direct method

Lp（a）

Apo A1 and Apo B were tested by immunoturbidimetic assay. Patient ’s sputum of real time

night and next morning was selected

acid-fast staining and microscopic examination were done. The results were showed by--

1+

2+

3+

4+. Results:（1）Compared with those of healthy controls

TC

TG

HDL-C

LDLC

Apo A1 and Apo B of single-tuberculosis group were reduced（Z=-5.941

-3.733

-4.170

-6.213

-4.557

-4.022

respectively;P=0.000）

while Lp（a）was raised（Z=-2.399

P=0.016）.（2）Compared with those of healthy controls

TC

TG

HDL-C

LDL-C

Apo A1 and Apo B of tuberculosis & pneumonia group were reduced（Z=-6.894

-3.676

-5.796

-6.287

-5.799

-4.321

respectively

P=0.000）

while Lp（a）was raised（Z=-2.888

P=0.004）.（3）Compared with those of single-tuberculosis group

TC

HDL-C

LDL-C and Apo A1 of tuberculosis & pneumonia group were reduced（Z=-5.624

-4.169

-2.237

-4.328

respectively;0.000

0.000

0.025

0.000

respectively）.（4）Sputum smear results of single-tuberculosis group were related with Apo A1（rs=-0.319

P=0.000）

while sputum smear results of tuberculosis & pneumonia group were related with HDL-C and Apo A1（rs=-0.175

-0.302

respectively;P=0.002

0.000

respectively）. Conclusion:（1）TC

TG

HDL-C

LDL-C

Lp（a）

Apo A1

and Apo B are auxiliary test for the diagnosis of pulmonary tuberculosis.（2）TC

HDL-C

LDL-C and Apo A1 can be used to differentiate pulmonary tuberculosis and pulmonary tuberculosis &bacterial pneumonia.（3）Apo A1 is expected to be the disease severity standard for pulmonary tuberculosis

while HDL-C and Apo A1 are expected to be the disease severity standards for pulmonary tuberculosis & bacterial pneumonia.