Value of carbohydrate antigen 125, human chorionic gonadotropin and progesterone in predicting pregnancy outcome in patients with threatened abortion at early stage
Huang Ye, Chen Wei, Diao Juncheng. Value of carbohydrate antigen 125, human chorionic gonadotropin and progesterone in predicting pregnancy outcome in patients with threatened abortion at early stage[J]. Journal of Chongqing Medical University, 2016,41(3):253-256.
Huang Ye, Chen Wei, Diao Juncheng. Value of carbohydrate antigen 125, human chorionic gonadotropin and progesterone in predicting pregnancy outcome in patients with threatened abortion at early stage[J]. Journal of Chongqing Medical University, 2016,41(3):253-256. DOI: 10.13406/j.cnki.cyxb.000821.
Objective:To research the value of carbohydrate antigen 125(Ca125)
human chorionic gonadotropin(HCG)and progesterone(P)value in the prediction of pregnancy outcome of patients with threatened abortion at early stage. Methods:Totally 267 patients with threatened abortion at 5-7 weeks of gestation in Jiangxi Traditional Chinese Medicine Hospital from January 2013 to De cember 2013 were selected according to inclusion and exclusion criteria. Ninety-six patients with early pregnancy were divided into continued pregnancy group and inevitable abortion group by pregnancy result
while the early pregnancy testers were taken as normal pregnancy group. Ca125
HCG and P levels of patients with early pregnancy were detected and follow- up was conducted till the 12 th week of pregnancy. Sensitivity and specificity of Ca125
HCG
and P in the diagnosis of threatened abortion were analyzed.Results:Levels of Ca125 were higher in normal pregnancy group and continued pregnancy group than in inevitable abortion group
with significant differences among groups(P<0.001)At 5-7 weeks of gestation
the sensitivity of Ca125 in the diagnosis of inevitable abortion was 76.3% and specificity was 68.5%. Conclusion:Ca125
HCG and P have high diagnostic value in the prediction of inevitable abortion.