Objective:To analyze the species and clinical features of dermatomyositis(DM) and polymyositis(PM) complicated with lung diseases. Methods:Totally 54 cases of hospitalized DM/PM patients with pulmonary disease

who are admitted to the First Affiliated Hospital of Chongqing Medical University from January 2011 to November 2014 were taken as the objects. The general condition

clinical manifestation

laboratory examination

pulmonary function

imaging

treatment and prognosis were retrospectively analyzed.Results:DM/PM complicated with interstitial lung disease(ILD) occurs most frequently

whose common symptoms are cough

shortness of breath

elevated erythrocyte sedimentation rate(ESR)

C-reactive protein(CRP)

creatine kinase(CK) and ferritin as well as positive anti-Jo-1 antibody;the abnormal lung function mainly displays as diffused and restrictive ventilatory dysfunction;ground glass is the most common sign in thoracic CT. Cutaneous vasculitis and malignant erythema are obvious in DM/PM complicated with lung cancer;80% patients has abnormally elevated CK and negative anti-Jo-1 antibody. DM/PM complicated with pneumomediastinum is a rare but serious complication;66.7% patients have significant skin vasculitis. All patients are young men

who have lower CK

increased ESR

negative anti-Jo-1 antibody. Conclusion :DM/PM patients complicated with lung disease are associated with corresponding inflammatory and immunological indexes.