Objective:To observe the clinical efficacy of postoperative electronic irradiation combined with brachytherapy by

192

Ir for keloid. Methods:Totally 203 cases of keloid from January 2003 to December 2013 were divided into observation group（n=105

group A） and control group（n=98

group B）. Radiotherapy was given within 24 h after operation in 105 patients with keloid. The lesions were treated by 4-6 Me V-E by Varian 2 300C/D medical linear accelerator. In group A

radiotherapy was given once a day（5 times a week） with a dosage of 2 Gy each time（10 Gy for 5 times）;then electronic irradiation combined with brachytherapy by192 Ir was given twice a week（2 times in total） with a dosage of 5 Gy each time（10 Gy for 2 times）. In group B

treatment was given once a day（5times a week） with a dosage of 4 Gy each time（20 Gy 1for 5 times）. Darzi’s criteria were used to do the evaluation and statistical analysis was made using SPSS 13.0. χ

2

test was used and P

<

0.05 was considered statistical significant. Results :Postoperative follow-up lasted for 12 months or more in 105 patients

65 were cured 33 were excellent;the effective rate was 93.33%;7 cases were invalid. Conclusion:Postoperative electronic line in keloid by normal radiotherapy combined with late course

192

Ir brachytherapy is effective in improving the cure rate and reducing recurrence rate.