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老年结直肠癌术后胃肠功能障碍的影响因素及预测模型
Influencing factors and prediction model of postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer
- 局解手术学杂志 2023年32卷第10期 页码：906-909
- 作者机构：
四川大学华西医院广安医院肛肠科，四川 广安 638000
- 作者简介：
董馨瑶，E-mail：49730667@qq.com
- 基金信息：四川省卫生和计划生育委员会科研项目(18PJ422)
DOI：10.11659/jjssx.12E022015
中图分类号： R735.3+5纸质出版日期：2023-10-25，
收稿日期：2022-12-02，
扫 描 看 全 文
石丽,夏茂玲,严茜等.老年结直肠癌术后胃肠功能障碍的影响因素及预测模型[J].局解手术学杂志,2023,32(10):906-909.
SHI Li,XIA Mao-ling,YAN Qian,et al.Influencing factors and prediction model of postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(10):906-909.
石丽,夏茂玲,严茜等.老年结直肠癌术后胃肠功能障碍的影响因素及预测模型[J].局解手术学杂志,2023,32(10):906-909. DOI： 10.11659/jjssx.12E022015.
SHI Li,XIA Mao-ling,YAN Qian,et al.Influencing factors and prediction model of postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(10):906-909. DOI： 10.11659/jjssx.12E022015.
摘要
目的
2
探讨老年结直肠癌患者术后胃肠功能障碍的影响因素，建立胃肠功能障碍预测模型。
方法
2
选择2020年2月至2022年2月我院收治的200例老年结直肠癌手术患者作为研究对象，根据术后胃肠功能I-FEED评估结果分为障碍组及非障碍组。通过单因素分析及
Logistic
回归分析，筛选老年结直肠癌患者术后胃肠功能障碍的影响因素。基于危险因素建立风险预测模型，通过受试者工作特征（
ROC
）曲线评估模型的预测价值。
结果
2
200例患者中，75例发生术后胃肠功能障碍，发生率为32.50%，年龄大、吸烟史、心血管疾病、术前贫血、术前CA19-9水平高、手术时间长及术前不完全肠梗阻是老年结直肠癌患者术后发生胃肠功能障碍的危险因素（
P
<
0.05），术前营养评分是保护因素（
P
<
0.05）。
H
-
L
检验结果显示，预测模型区分度较好。
结论
2
老年结直肠癌术后胃肠功能障碍的影响因素较多，应针对影响因素采取干预措施，以减少术后胃肠功能障碍的发生，改善手术预后。基于上述因素构建的预测模型具有较好的预测价值。
Abstract
Objective
2
To investigate the influencing factors of postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer， and establish a prediction model of gastrointestinal dysfunction.
Methods
2
A total of 200 elderly patients underwent surgery for colorectal cancer in our hospital from February 2020 to February 2022 were selected as the research objects. According to the I-FEED evaluation results of postoperative gastrointestinal function， they were divided into the dysfunction group and the non-dysfunction group. Univariate analysis and
Logistic
regression analysis were used to screen the influencing factors of postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer. A risk prediction model was constructed based on the risk factors， and the predictive value of the model was evaluated by
receiver operating characteristic
（
ROC
） curve.
Results
2
Among the 200 patients， 75 cases developed postoperative gastrointestinal dysfunction， the incidence rate was 32.50%. Older age， smoking history， cardiovascular disease， preoperative anemia， high preoperative CA19-9 level， long operation time and incomplete intestinal obstruction were the risk factors for postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer （
P
<
0.05）， and preoperative nutritional score was the protective factor （
P
<
0.05）.
H-L
test results showed that the prediction model had good discrimination.
Conclusion
2
There are many influencing factors that affect postoperative gastrointestinal dysfunction in elderly patients with colorectal cancer， and intervention measures should be taken according to the influencing factors to reduce the incidence of postoperative gastrointestinal dysfunction and improve the surgical prognosis. The predictive model constructed based on the above factors has good predictive value.
关键词
老年结直肠癌胃肠功能障碍影响因素预测模型
Keywords
elderlycolorectal cancergastrointestinal dysfunctioninfluencing factorpredictive model
references
Zheng H，Liu H，Ge Y，et al.Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in colorectal cancer［J］.Cancer Cell Int，2021，21（1）：119-131.doi：10.1186/s12885-022-10332-whttp://dx.doi.org/10.1186/s12885-022-10332-w.
齐凡，虞晓红.急诊腹部手术后胃肠道功能障碍研究现状［J］.临床急诊杂志，2020，21（4）：334-340.doi：10.13201/j.issn.1009-5918.2020.04.017http://dx.doi.org/10.13201/j.issn.1009-5918.2020.04.017.
杨战锋，陈天然，吴万庆，等.腹腔镜直肠癌前切除术后患者胃肠功能恢复的影响因素分析［J］.医学研究杂志，2022，51（4）：104-108.doi：10.11969/j.issn.1673-548X.2022.04.024http://dx.doi.org/10.11969/j.issn.1673-548X.2022.04.024.
Woodfield JC，Beshay NM，Pettigrew RA，et al.American Society of Anesthesiologists classification of physical status as a predictor of wound infection.［J］.ANZ J Surg，2007，77（9）：738-741.doi：10.1111/j.1445-2197.2007.04220.xhttp://dx.doi.org/10.1111/j.1445-2197.2007.04220.x.
Alsharqawi N，Alhashemi M，Kaneva P，et al.Validity of the I-FEED score for postoperative gastrointestinal function in patients undergoing colorectal surgery［J］.Surg Endosc，2020，34（5）：2219-2226.doi：10.1007/s00464-019-07011-6http://dx.doi.org/10.1007/s00464-019-07011-6.
张雪逸，王迎斌.术后胃肠功能评估及预防术后胃肠功能障碍的研究进展［J］.北京医学，2021，43（4）：331-333.doi：10.15932/j. 0253-9713.2021.04.011http://dx.doi.org/10.15932/j.0253-9713.2021.04.011.
Tomita R，Sakurai K，Fujisaki S，et al.Relationship between inter-digestive migrating motor complex and quality of life in patients after conventional distal gastrectomy for gastric cancer［J］.Hepatogastroenterology，2012，59（119）：2037-2041.doi：10.5754/hge12334http://dx.doi.org/10.5754/hge12334.
李晗，李畅，苏妍卓，等.肠梗阻导管治疗结直肠癌手术后早期炎症性肠梗阻［J］.中国普外基础与临床杂志，2021，28（8）：1078-1080.doi：10.7507/1007-9424.202012025http://dx.doi.org/10.7507/1007-9424.202012025.
李丽，李燕梅，冯丽娟，等.老年术后早期炎性肠梗阻临床疗效观察［J］.现代消化及介入诊疗，2020，25（2）：227-229.doi：10.3969/j.issn.1672-2159.2020.02.023http://dx.doi.org/10.3969/j.issn.1672-2159.2020.02.023.
Arunachala Murthy T，Chapple LS，Lange K，et al.Gastrointestinal dysfunction during enteral nutrition delivery in intensive care unit （ICU） patients：risk factors，natural history，and clinical implications.A post-hoc analysis of The Augmented versus Routine approach to Giving Energy Trial （TARGET）［J］.Am J Clin Nutr，2022，116（2）：589-598.doi：10.1093/ajcn/nqac113http://dx.doi.org/10.1093/ajcn/nqac113.
查震球，李蕊，胡明军，等.吸烟状况与胃癌患者发病年龄及其直接医疗费用的关系分析［J］.中华流行病学杂志，2020，41（9）：1482-1486.doi：10.3760/cma.j.cn112338-20190927-00706http://dx.doi.org/10.3760/cma.j.cn112338-20190927-00706.
于艳，李红.体检人群胃黏膜肠化生的筛查及其相关危险因素评估［J］.解放军医学院学报，2020，41（6）：555-558.doi：10. 3969/j.issn.2095-5227.2020.06.003http://dx.doi.org/10.3969/j.issn.2095-5227.2020.06.003.
Ohlsson B.The role of smoking and alcohol behaviour in management of functional gastrointestinal disorders［J］.Best Pract Res Clin Gastroenterol，2017，31（5）：545-552.doi：10.1016/j.bpg.2017.09.006http://dx.doi.org/10.1016/j.bpg.2017.09.006.
Berkowitz L，Schultz BM，Salazar GA，et al.Impact of cigarette smoking on the gastrointestinal tract inflammation：opposing effects in crohn's disease and ulcerative colitis［J］.Front Immunol，2018，30（9）：74.doi：10.3389/fimmu.2018.00074http://dx.doi.org/10.3389/fimmu.2018.00074.
杨华，肖刚，吴国举，等.CEA和CA19-9在结直肠癌患者中的诊断及预后价值［J］.中国现代普通外科进展，2017，7（20）：20-23.doi：10.3969/j.issn.1009-9905.2017.07.005http://dx.doi.org/10.3969/j.issn.1009-9905.2017.07.005.
唐小兵，张超，周涛，等.不同CO2压力对腹腔镜直肠癌根治术患者术中应激反应及胃肠功能的影响［J］.局解手术学杂志，2020，29（4）：308-312.doi：10.11659/jjssx.01E020087http://dx.doi.org/10.11659/jjssx.01E020087.
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