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1.河北北方学院附属第一医院麻醉科,河北 张家口 075000
2.河北北方学院附属第一医院重症医学科,河北 张家口 075000
刘辉,E-mail:jsggll@126.com
纸质出版日期:2023-07-25,
收稿日期:2022-10-18,
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刘辉,熊立红,徐晓晴等.超声引导胸椎旁神经阻滞复合全身麻醉在开胸手术中的应用[J].局解手术学杂志,2023,32(07):621-624.
LIU Hui,XIONG Li-hong,XU Xiao-qing,et al.Application of ultrasound-guided paravertebral nerve block combined with general anesthesia in thoracotomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(07):621-624.
刘辉,熊立红,徐晓晴等.超声引导胸椎旁神经阻滞复合全身麻醉在开胸手术中的应用[J].局解手术学杂志,2023,32(07):621-624. DOI: 10.11659/jjssx.10E022091.
LIU Hui,XIONG Li-hong,XU Xiao-qing,et al.Application of ultrasound-guided paravertebral nerve block combined with general anesthesia in thoracotomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(07):621-624. DOI: 10.11659/jjssx.10E022091.
目的
2
探讨超声引导胸椎旁神经阻滞复合全身麻醉在开胸手术中的应用效果。
方法
2
选取2018年5月至2020年5月本院收治的择期行开胸手术患者60例,随机将其分为观察组30例(给予超声引导胸椎旁神经阻滞复合全身麻醉)和对照组30例(给予单纯全身麻醉)。记录并比较2组患者不同时间点心率、平均动脉压(MAP)、VAS评分及氧化应激反应指标[去甲肾上腺素(NE)、促肾上腺皮质激素(ACTH)、皮质醇(Cor)、超氧化物歧化酶(SOD)、丙二醛(MDA)],比较2组术后不良反应发生情况。
结果
2
观察组术后2 h、6 h、12 h、24 h心率及MAP均显著低于对照组(
P
<
0.05)。2组术后2 h、6 h、12 h、24 h的VAS评分逐渐降低(
P
<
0.05),而观察组术后VAS评分均显著低于对照组(
P
<
0.05)。2组术后24 h血清NE、ACTH、Cor及MDA水平均显著升高(
P
<
0.05),而SOD水平显著降低(
P
<
0.05);观察组患者术后24 h血清NE、ACTH、Cor、SOD及MDA水平均显著低于对照组(
P
<
0.05)。观察组术后不良反应总发生率明显低于对照组(
P
<
0.05)。
结论
2
超声引导胸椎旁神经阻滞复合全身麻醉对行开胸手术患者的心率、MAP影响较小,能明显减轻患者术后疼痛及氧化应激反应,安全性较高。
Objective
2
To explore the application effect of ultrasound-guided paravertebral nerve block combined with general anesthesia for patients undergoing thoracotomy.
Methods
2
A total of 60 patients underwent elective thoracotomy in our hosipital form May 2018 to May 2020 were selected, then randomly divided into the observation group 30 cases(given ultrasound-guided paravertebral nerve block combined with general anesthesia) and the control group 30 cases (only given general anesthesia).The heart rate,mean arterial pressure(MAP),VAS score and the indexes of oxidative stress response[noradrenaline(NE),adrenocorticotrophic hormone(ACTH),cortisol(Cor),superoxide dismutase(SOD),malondialdehyde(MDA)] at different time points were recorded and compared.The postoperative adverse reactions of the two groups were compared.
Results
2
The heart rate and the MAP at 2 hours, 6 hours, 12 hours and 24 hours after surgery of the observation group were significantly lower than those of the control group (
P
<
0.05).The VAS scores of the two groups gradualy decreased from 2 hours to 24 hours after operation,the VAS scores at different time points after surgery of the observation group were all significantly lower than those of the control group (
P
<
0.05).The serum NE, ACTH, Cor and MDA levels at 24 hours after surgery of the two groups increased significantly(
P
<
0.05), while the serum SOD levels decreased significantly (
P
<
0.05);The serum NE, ACTH, Cor, SOD and MDA levels at 24 hours of the patients in the observation group were significantly lower than those in the control group (
P
<
0.05). The total incidence of adverse reactions in the observation group was significantly lower than that in the control group(
P
<
0.05).
Conclusion
2
Ultrasound-guided paravertebral nerve block combined with general anesthesia has little effect on heart rate and MAP of patients underwent thoracotomy,which can significantly relieve the postoperative pain and oxidative stress,with high safety.
超声胸椎旁神经阻滞全身麻醉开胸手术
ultrasoundparavertebral nerve blockgeneral anesthesiathoracotomy
周瑜,代俊超,毕小波.超声引导联合全身麻醉对高龄肺癌肺叶切除术患者的术中镇痛效果及术后早期转归的影响[J].中国肿瘤临床,2021,48(4):174-179.doi:10.3969/j.issn.1000-8179.2021.04.076http://dx.doi.org/10.3969/j.issn.1000-8179.2021.04.076.
Mona MM,Mohamed SE.Paravertebral block versus intercostal nerve block in non-intubated uniportal video-assisted thoracoscopic surgery:a randomised controlled trial[J].Heart Lung Circ,2020,29(5):800-807.doi:10.1016/j.hlc.2019.04.013http://dx.doi.org/10.1016/j.hlc.2019.04.013.
金胜,余正文.胸椎旁神经阻滞复合全身麻醉在肺癌根治术患者术后自控静脉镇痛中的应用研究[J].癌症进展,2019,17(4):452-455.doi:10.11877/j.issn.1672-1535.2019.17.04.22http://dx.doi.org/10.11877/j.issn.1672-1535.2019.17.04.22.
Özlem T,Nükhet S,Zerrin S,et al.Thoracic paravertebral block achieves better pain control than erector spinae plane block and intercostal nerve block in thoracoscopic surgery:a randomized study[J].J Cardiothor Vasc An,2021,35(10):2920-2927.doi:10.1053/j.jvca. 2020.11.034http://dx.doi.org/10.1053/j.jvca.2020.11.034.
曾凌竹,余云明.右美托咪定用于胸椎旁神经阻滞对老年开胸手术患者氧化应激及炎性反应的影响[J].现代中西医结合杂志,2017,26(32):3629-3632.doi:10.3969/j.issn.1008-8849.2017.32.034http://dx.doi.org/10.3969/j.issn.1008-8849.2017.32.034.
王超,周新华,罗伟.超声引导下胸椎旁神经阻滞复合全身麻醉对乳腺癌患者术后镇痛及免疫细胞功能的影响[J].现代肿瘤医学,2021,29(22):3990-3993. doi:10.3969/j.issn.1672-4992. 2021.22.022http://dx.doi.org/10.3969/j.issn.1672-4992.2021.22.022.
路凯,陈海燕,徐瑞芬,等.超声引导下胸椎旁神经阻滞对开胸手术患者应激反应指标水平、术后镇痛效果的影响[J].临床医学研究与实践,2021,6(21):53-55.doi:10.19347/j.cnki.2096-1413.202121017http://dx.doi.org/10.19347/j.cnki.2096-1413.202121017.
胡晓旻,刘刚,刘超,等.超声引导下胸椎旁神经阻滞复合全身麻醉对老年肺癌患者应激反应和炎性反应及血流动力学的影响[J].中国老年学杂志,2017,37(24):6111-6113.doi:10.3969/j.issn.1005-9202.2017.24.046http://dx.doi.org/10.3969/j.issn.1005-9202.2017.24.046.
徐祝红,邹珉,王良萍.超声引导下椎旁神经阻滞复合全身麻醉对胸腔镜肺大泡切除术应激反应的影响[J].中国当代医药,2017,24(20):134-137.doi:10.3969/j.issn.1674-4721.2017.20.043http://dx.doi.org/10.3969/j.issn.1674-4721.2017.20.043.
乔飞,汪瑁,展希,等.超声引导下椎旁阻滞在开胸手术后镇痛的临床应用[J].昆明医科大学学报,2017,38(6):87-91.
王钱荣,何焕钟,汪卫星,等.超声引导单次胸椎旁阻滞应用于全麻下老年胸腔镜手术的临床疗效[J].中国老年学杂志,2017,37(7):1700-1701.doi:10.3969/j.issn.1005-9202.2017.07.057http://dx.doi.org/10.3969/j.issn.1005-9202.2017.07.057.
Yar LY,John WW,Kevin MB,et al.Randomized prospective study evaluating single-injection paravertebral block,paravertebral catheter,and thoracic epidural catheter for postoperative regional analgesia after video-assisted thoracoscopic surgery[J].J Cardiothor Vasc An,2020,34(7):1870-1876.doi:10.1053/j.jvca.2020.01.036http://dx.doi.org/10.1053/j.jvca.2020.01.036.
朱 梅,范天琼.胸椎旁神经阻滞复合全身麻醉在老年开胸手术患者中的应用效果观察[J].中国医药科学,2021,11(7):180-183.doi:10.3969/j.issn.2095-0616.2021.07.049http://dx.doi.org/10.3969/j.issn.2095-0616.2021.07.049.
陈中刚,陈林,谭志敏.超声引导胸椎旁神经阻滞复合全身麻醉对胸腔镜肺癌根治术患者术中镇痛药物使用量及氧化应激反应的影响[J].广州医科大学学报,2020,48(6):45-48.doi:10.3969/j.issn.2095-9664.2020.06.11http://dx.doi.org/10.3969/j.issn.2095-9664.2020.06.11.
喻耀华.胸椎旁神经阻滞复合全身麻醉对胸腔镜肺癌根治术患者血流动力学和应激反应的影响[J].中国现代医生,2018,56(33):117-120.
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