Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis

Guangyao Wei; Jia Liu; Jie Lan; Guangyu Ji; Huize Xia; Zhiqun Zhao; Zhaoxue Yu; Rong Sun; Chuanzhao Zhang; Haiquan Lu

doi:10.1016/j.gendis.2023.02.034

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Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis

Rapid Communications | 更新时间：2024-02-04

- Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis
- Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis
- Genes & Diseases 2023年1卷第6期页码：2195-2198
- 作者机构：
  
  1. The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University,Shandong,Jinan,China,250012
  2. Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University,Shandong,Jinan,China,250012
  3. Department of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University,Sichuan,Chengdu,China,610041
  4. Shandong Zhongke Institute for Regenerative Medicine,Shandong,Jinan,China,250012
  5. Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,Guangdong,Guangzhou,China,510080
  6. Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University,Shandong,Jinan,China,250012
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.02.034
  中图分类号：
- 纸质出版日期：2023，
  
  网络出版日期：2023-11-1，
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Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis[J]. Genes & Diseases, 2023,1(6):2195-2198.

Guangyao Wei, Jia Liu, Jie Lan, et al. Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis[J]. Genes & Diseases, 2023,1(6):2195-2198.
Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis[J]. Genes & Diseases, 2023,1(6):2195-2198. DOI： 10.1016/j.gendis.2023.02.034.

Guangyao Wei, Jia Liu, Jie Lan, et al. Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis[J]. Genes & Diseases, 2023,1(6):2195-2198. DOI： 10.1016/j.gendis.2023.02.034.

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1 W.D. Foulkes, I.E. Smith, J.S. Reis-FilhoTriple-negative breast cancer N Engl J Med, 363 (20) (2010), pp. 1938-1948

2 S. Doll, B. Proneth, Y.Y. Tyurina, et al.ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition Nat Chem Biol, 13 (1) (2017), pp. 91-98

3 Q. Zheng, M. Zhang, F. Zhou, et al.The breast cancer stem cells traits and drug resistance Front Pharmacol, 11 (2020), p. 599965

4 G.L. SemenzaThe hypoxic tumor microenvironment: a driving force for breast cancer progression Biochim Biophys Acta, 1863 (3) (2016), pp. 382-391

5 S.J. Dixon, B.R. StockwellThe hallmarks of ferroptosis Annu Rev Cancer Biol, 3 (2019), pp. 35-54

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