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Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine,Shanghai,China,201203
纸质出版日期:2023,
网络出版日期:2023-11-1,
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Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment[J]. Genes & Diseases, 2023,1(6):2414-2424.
Qianqian Zhou, Yanhua Chen, Ruolei Wang, et al. Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment[J]. Genes & Diseases, 2023,1(6):2414-2424.
Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment[J]. Genes & Diseases, 2023,1(6):2414-2424. DOI: 10.1016/j.gendis.2022.11.016.
Qianqian Zhou, Yanhua Chen, Ruolei Wang, et al. Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment[J]. Genes & Diseases, 2023,1(6):2414-2424. DOI: 10.1016/j.gendis.2022.11.016.
The ongoing global pandemic of coronavirus disease 2019 (COVID-19)
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has resulted in over 570 million infections and 6 million deaths worldwide. Early detection and quarantine are essential to arrest the spread of the highly contagious COVID-19. High-risk groups
such as older adults and individuals with comorbidities
can present severe symptoms
including pyrexia
pertussis
and acute respiratory distress syndrome
on SARS-CoV-2 infection that can prove fatal
demonstrating a clear need for high-throughput and sensitive platforms to detect and eliminate SARS-CoV-2. CRISPR-Cas13
an emerging CRISPR system targeting RNA with high specificity and efficiency
has recently drawn much attention for COVID-19 diagnosis and treatment. Here
we summarized the current research progress on CRISPR-Cas13 in COVID-19 diagnosis and treatment and highlight the challenges and future research directions of CRISPR-Cas13 for effectively counteracting COVID-19.
COVID-19CRISPR-Cas13DiagnosisSARS-Cov-2Treatment
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