Translational medicine emerging as a new concept in medical field， concentrates on the integration of theory and practice， and the conjunction of basic medical science and clinical medicine. Barriers between the basic medicine and clinical medicine existing in medical education in China make students possess limited intelligence， narrow perspectives and low creativity etc.， causing the medical teaching unable to conform to the demand of translational medicine. The article introduces the basic conception of translational medicine and the necessity of medical teaching reform， the meth-ods of promoting teaching reform by integrating the curriculum systems， bettering experimental teach-ing systems， strengthening humanities education， improving faculty construction and optimizing eval-uation system for students.