Objective　To investigate clinical interns' mastery and understanding status of medical core systems in order to provide reference for formulating training programs. Methods　The questionnaires including medical core systems trained and self-assessment and test paper were de-signed. Then survey was carried out among 188 clinical interns of Grade 2009 of Zunyi Medical Col-lege at the end of training. All data were obtained

collected and analyzed with Excel and a SPSS 17.0.The result was described with percentage. Results　①78/41.34% and 117/62.33% clinical interns accepted training of medical core systems respectively before or during clinic training. 74/39.43% hos-pitals or 70/37.30% departments were systematically trained by medical core systems and the propor-tion of teachers who systematically or non-systematically explained medical core systems for clinical interns was 42/22.29% and 61/32.37% respectively. ②The clinical interns who mastered first diagnosis responsibility systems

patient communication system

and systems of discussing difficult cases were 178/94.68%

178/90.43% or 168/89.36%. The clinical interns who mastered rescue systems in critically ill patients

surgical classification management systems and audit system in clinical blood transfusion were 84/44.68%

67/35.64% or 34/18.28% respectively. ③8/6.90% interns fully grasped the core system of the medical situation. 165/87.71% and 165/83.43% clinical interns believed medical core systems should be mastered and 157 interns (83.43%) thought that mastering medical core system can help them better adapt to clinical medical work. Conclusion　Systematic training of medical core system should be enhanced for clinical interns and mastering medical core systems is better for their future.