Objective　To investigate the learning cognition and demand of medical college undergraduates for statistics course and its teaching effect

so as to better carry out the teaching work of statistics course and provide better teaching experience. Methods　A total of 319 undergraduates from 11 medical universities and colleges who had finished statistics course were involved to conduct a questionnaire survey by using the online questionnaire survey method. Results　The senior undergraduates (grade 3

grade 4

grade 5) participated in statistic course accounted for a large proportion of 94.60%; 61.90% subjects thought the course was difficult. For undergraduate public health majors and non-public health majors

more than 90% considered that it was necessary to set up the corresponding statistics courses; about 4.00% did not like the corresponding statistics courses; 75.87%

69.52% and 50.16% thought that teaching method

teaching content and class schedule were the main reason influencing the statistics course

respectively; and 61.9% thought that case teaching was the best way to master the course. The results also showed that all subjects had a common comprehending of statistical theory and a poor comprehending of software operation skills. About 90% of the research subjects had requirement for theoretical knowledge or software operation. Conclusion　Colleges and universities should make theoretical courses more targeted

increase the proportion of case teaching

strengthen the teaching of software operation skills and appropriately set up corresponding training courses

to solve the problem that it is difficult to achieve satisfactory teaching effect.