Objective　To understand the effect of student standardized patient-case teaching in orthopedic surgery. Methods A total of 120 clinical medicine students were selected， and they were ran-domly assigned to be research group（n=60）and control group（n=60）， as students standardized pa-tient， 10 clinical medicine students and postgraduate students of orthopedic surgery were selected， and standardized patient-case teaching was applied to the students in research group while traditional case teaching was applied to students in control group. After teaching， the teaching effect and survey the feed-back information about teaching form students were evaluated. Results　Total mark of effect evaluation of 2 groups is 83.50±6.55 and 71.11±6.57， and both operational score and knowledge study achieve-ments of research group were better than control group（P<0.01）， over 80% research group students ef-fect evaluation being positive. Conclusion　Student standardized patient-case teaching is helpful to im-proving students' study in orthopedic surgery and the teaching effect is remarkable.