Objective To construct a method for simulation scene teaching of cardio-pulmonary resuscitation (CPR). Methods Rescue processes for different cardiac arrest types were programmed by taking XinJiang Medical University clinical skill center as the backing and by using Norway production of CPR SIMMAN. Forty students were divided into 2 groups to do the practice and self-made questionnaire survey was conducted after the practice. Data of questionnaires were descriptively analyzed by SPSS15.0. Results A hierarchical training program combined with simulation scene teaching can most effectively control key points of CPR (75.56%). Searching for references, group discussion and report under the guidance of teachers and based on clinical case were the best way to teach CPR(97.78%). Case study under the guidance of teachers was the most fruitful way(73.33%). CPR simulation scene teaching and hierarchical teaching were combined well (75.56%). Conclusions Construction of CPR simulation scene teaching fully embodies the continuity and sustainability of emergency teaching. It can effectively improve teaching methods and teaching quality of emergency medicine as well as enhance students' problem-solving abilities.