Objective　To explore the efficacy of the case and scenario teaching method in the neurosurgery practice teaching. Methods　By cluster sampling， 153 nursing students underwent rotary practice in neurosurgery department in People's Hospital of Three Gorges University from September 2011 to July 2012 were trained with the case and scenario teaching method. Scenario simulation train-ing combined with case playback teaching was used in practice teaching. At the end of the internship， nursing students' satisfaction was investigated and their operational capacity was evaluated. Self-de-signed questionnaire was adopted to evaluate satisfaction. Operational capacity evaluation scores of nursing students were divided into several parts： basic operation examination（30%）， specialized operation（30%）， professional theory（30%） and teacher evaluation（10%）. Data were analyzed using Excel spreadsheet for entry. Countif and Count function formula were used to calculate eligibility and the passing rate. Results　Nursing students had high evaluation on case playback teaching methods. By this method， 153（100%） nursing students considered that the learning initiative was improved. At the end of the internship， passing rates of basic operation examination， specialized operation， profes-sional theory were 98.69%（151/153）， 96.73%（148/153） and 100% while the total passing rate was 100%. Conclusion　The case and scenario teaching method could develop the study positivity and practice ability of nursing students and can enhance the internship efficacy.