Objective　To establish a two-way evaluation system and to explore the application effect of two-way evaluation method in clinical nursing teaching. Methods　We carried out two-way evaluation and individual evaluation test to 40 nursing students practicing in the Department of Inter-nal Medicine of our hospital in 2012 and 20 teachers responsible for teaching. By using the envelope method， nursing students and teachers were randomly divided into two groups， with 20 nursing stu-dents and 10 teachers in the experimental group and the control group respectively. Students' assess-ment form and the teachers teaching level evaluation table were made， and teachers of both group gave scores every two weeks to the nursing students by nursing students' evaluation sheet， and the score of feedback were given to the nursing students in experimental group. At the same time， the nursing students in experimental group gave scores every two weeks to the teachers of the same group by the teachers' teaching evaluation sheet， and feedback the results. SPSS 13.0 was used to make statistical analysis and the scores of nursing students and teachers of both groups and the last scores were com-pared with paired sample T test of mean. The results of the experimental group and the control group in the same period were compared with two independent samples T test of mean. Results　Comparing the nursing students' scores of both groups with the scores they themselves got last time， the scores of the fourth， sixth， and the eighth week were statistically significant（P<0.05）and comparing the exper-imental group teachers' score with and the scores they themselves got last time， the scores of the fourth， sixth， and the eighth week were also statistically significant（P<0.05）； from the fourth week on， nursing students' scores in experimental group compared with those in control group in the same period， show the differences statistically significant（P<0.05）. Conclusion　Two-way evaluation system is beneficial to improving the enthusiasm and initiative of the teachers and students. Two-way evalua-tion and bidirectional interaction are helpful to timely detection of problems and improvement and can effectively improve the quality of clinical nursing teaching in internal neurological medicine.