Objective　To evaluate the effects of applying clinical pathway（CP） in clinical teaching of gynecology and obstetrics. Methods　Totally 200 clinical specialist interns selected for the study were randomly divided into two groups（each 100）， respectively， using CP teaching and tradi-tional teaching. After the internship， professional assessment（clinical skills assessment， theory test， the respondent）were conducted to two groups of students and their professional examination scores were compared， while questionnaires were conducted in the CP teaching group. All date were analyzed by SPSS 17.0 software. Chi-square test was used for enumeration date while t test was used for mea-surement data. Results　CP teaching team of professional test results [（80.01 ± 9.34） vs. （72.37 ± 10.79）]， the passing rate（96% vs. 87%） were superior to the traditional teaching group（P=0.000 and 0.022）. The questionnaire showed that： applying CP in clinical teaching of obstetrics and gynecology can improve interns' learning enthusiasm and initiative， improve their comprehensive analysis ability， clinical thinking ability， practical ability and many other capabilities and it got about 90% of interns' recognition. Conclusions　The application of the CP in clinical teaching of obstetrics and gynecology can help enhance the teaching effectiveness， standardize the teaching process， and improve the qual-ity of teachers teaching gynecology and obstetrics.