[Abstract] Objective To explore the effect and method of the theory teaching of general practice course for eight-year program of clinical medical students. Methods Set up the course of General Medicine for 87 students from two grades in their fourth school year. All of them attended a closed-book examination when finished the lectures. Analyze the test scores and a questionnaire was surveyed. The satisfaction rates

necessity and the suggestion of teaching and assessment were collected from the questionnaire. Results The examination results of the two grade students were 80.92 ±7.26 and 83.76±5.75 respectively（t=1.99，P=0.05）; The satisfaction rate is 40.2%（35/87）; Necessity of the courses is between 3.6 to 4.1(5-point-Likert-scale).The way of teaching method students choose is different by course content. Conclusion The theory teaching of general practice course for eight-year program of clinical medical students needs more reform from curriculum designing

teaching methods

faculty training and evaluation methods.