[Abstract] Objective To evaluate the teaching effects of applying clinical pathway in clinical practice teaching of neurology. Methods Randomly divided undergraduate interns majoring in clinical medicine into clinical pathway teaching method group (n=34) and traditional teaching method group (n=34). Both groups were taught by senior physicians with the same teaching content and teaching material．Carried out a control study between the two groups in theoretical knowledge

operational skills and satisfaction degrees of teaching. Results The results of clinical pathway teaching method group in theoretical knowledge（55.2±3.70 vs 51.8±4.6） and operational skills （36.3±3.2 vs 31.3±2.19）were both significantly better than those of traditional teaching method group (p<0.05). The satisfaction degrees of teaching of clinical pathway teaching method group is relatively higher. Conclusions The clinical pathway teaching method enhances the scientific property and systematic property of teaching contents

obtaining a favorable teaching effect.