Objective　To explore the application effect of standardized patients (SP) combined with case-based learning (CBL) teaching model in endodontics for stomatology undergraduates. Methods　Forty-eight five-year stomatology undergraduates of Southern Medical University School of Stomatology were randomized into 2 groups

the experimental group and the control group. The experimental group adopted SP combined with CBL teaching model while the control group adopted LBL alone. After the course

the teaching effect was evaluated comprehensively. The data was analyzed by SPSS 20.0

and the differences of measurement data were compared with t test and chi-square test. Results　There was no significant difference in theoretical test scores between the two groups (P>0.05)

but the practical test results and comprehensive evaluation scores of the experimental group were significantly higher than those of the control group (P<0.01). The results of questionnaires indicated that students in the experimental group were much more satisfied with SP combined with CBL teaching model than the control group (88.8% vs. 56.3%). Conclusion　SP combined with CBL Teaching Model can achieves satisfactory teaching effect

and improves the learning efficiency of students.