A CLINICAL EVALUATION OF ADP-INDUCED BLOODP LATELET AGGREGATION FUNCTION WITH A COMPARISON OF ADP-TITER TEST TUBE METHOD AND AGGREGOMETER METHOD[J]. Journal of Chongqing Medical University, 1985,(2):107-111.
A CLINICAL EVALUATION OF ADP-INDUCED BLOODP LATELET AGGREGATION FUNCTION WITH A COMPARISON OF ADP-TITER TEST TUBE METHOD AND AGGREGOMETER METHOD[J]. Journal of Chongqing Medical University, 1985,(2):107-111.DOI:
ADP滴度试管法与聚集仪测定法检测血小板聚集功能在临床应用上的比较
摘要
本文就PAR及PAgT种方法
用ADP作致聚剂
对血小板聚集功能亢进与血小板聚集功能低下的两类患者在临床应用上进行比较。实验结果说明
对血小板聚集功能亢进的患者PAR试验敏感性比PAgT高
实验结果较客观
且能较好地反映血小板聚集的全过程。但标本脂血对实验结果有影响。PAgT尚具有一定的试验敏感性
由于其不需特殊仪器
简便易行
且不受标本脂血的影响
故仍不失为基层单位初步的筛选方法。在7例肝硬化患者中
由PAR所检出的血小板聚集功能低下的3例
PAgT却均正常
未能检出
故对肝硬化患者
不宜采用PAgT法。
Abstract
A clinical evaluation of ADP -induced blood platelet aggregation function in patients with hyperaggregation and hypoaggregation was investigated with a comparision of ADP-titer test tube method (PAgT) and platelet aggregorrister method (PAM). Oar datd revealed that platelet aggregation rate (PAR) 15 more ssasitive and objective in hyperaggregative patients than platelet aggregation test (PAgT)
The whole prosess of aggregation was also well reflected by PAR
but the result is easily affected by lipsmie specimen. Nevertheless
PAgT is still sensitive to some patients and was not influenced by lipstnia
Tt’as simple and easy to control and need not special apparatus
so that it may be used as screening test in general practice. Three out of seven patients with liver cirrhosis ware hypoaggregation with PAR but normal with PAgT. It is therefore not suitable for patients with liver cirrhosis to detect blood platelet aggregation function with PAgT.
关键词
滴度试管法聚集仪测定法
Keywords
titer test tube method(PAgT)Platelet Aggregometer method (PAM)