Research for determining the concentration of matrine in K562 culture-medium by reversed phase ion-pair HPLC[J]. Journal of Chongqing Medical University, 1997,(4).
Research for determining the concentration of matrine in K562 culture-medium by reversed phase ion-pair HPLC[J]. Journal of Chongqing Medical University, 1997,(4).DOI:
A reversed phase ion - pair high performance liquid chromatographic method was established for determining the concentration of matrine. The method was accurate and reliable with fine resolution and high sensitivity Matrine in medium can be seperated
determined and identified by this method. After extracted form the medium
the matrine was analysed preliminarily.We found that the concentration of matrine had a linear decline in the first day and was invariable during two days after that.