Objective: To make animal model of chronic myocardial infarction in rats. Methods: Wistar rats were anaesthetized with ketamine
sodium phenobarbital
atropine and lidocaine. Tracheotomy intubation and left anterior thoracotomy through 3
4 intercostal region were performed. Left anterior`descending coronary artery was ligated. Results: Rat mortality was 6.67% in 72 hours after operation. The survival rate was 78.1% beyond 3 weeks. Conclusion: This showed that the operation procedure was easy to perform with slight damage and high survival rate.