Objective: To compare the analgesic efficiency and adverse drug reactions of patient-controlled intravenous analgesia(PCIA) with Lornoxicam and Tramadol in patients undergoing the operation in cranio-cervical region.Methods: Forty ASAⅠ～Ⅱadult patients

who undergoing the operation in cranio-cervical region were randomly divided into two groups

both of which were diluted into 100ml with sodium and background 2ml/h

lockout time 15min

PCA bolus 0.5ml.The efficiency of analgesia provided by PCA was assessed by:(1)visual analogue scale(VAS) at 12

24

36h

48h after the operation;(2)adverse drug reactions such as nausea and vomiting

dizziness

respiratory depression and so on.Results: There was no statistically significant difference between the two groups in VAS score(P>0.05)

There were 2 cases of nausea and one case of vomit in Lornoxicam group

as compared with 8 cases of nausea and 4 cases of vomit in Tramadol group.The number of nausea is 2 vs 8(P<0.01)

voimiting 1 vs 4 in the two groups.Conclusion: Both lornoxicam and tramadol can be used in postoperative analgesia for patients undergoing oral maxillofacial surgery

of which lornoxicam has a better analgesia effect with less side effect and is a preferable choice.When used in patient-controlled intravenous analgesia

Lornoxicam has a safe and effect.condition

It can decrease the occurrence of side-effect each other when used with tramadol

especially nausea and vomit.