Objective:To compare the clinical effect of lateral and posterior approaches during the total hip replacement(THA) with Minimal-Incision Surgery(MIS).Methods:Twenty-three cases were performed with lateral approach

All were performed by the same surgeon.23 cases who had undergone a MIS THA with lateral approach were compared with 36 cases who had undergone MIS THA with the posterior approaches.The average follow-up period was 12 weeks.The patients were compared with respect to the length of the incision

surgical time

intra-operative blood loss

Harris hip score

component malpositioning

complications.Results:There were no differences between the two approaches with regard to the length of the skin incision

operating time

Harris hip score

component malpositioning and major complications.Statistically significant differences were found in two groups in terms of blood sedimentation and C-reaction protein.Conclusion:Both approaches can be effectively performed without increased risk of complications.Significant benefits of posterior approaches include less soft tissue damage.