Objective:To explore the possibility of fresh amniotic membrane transplantation for reconstruction of ocular surface with acute burn and evaluate the effect.Method:20 cases(24 eyes)due to acute burn of ocular surface were performed fresh amniotic membrane transplantation.All patients were followed up for 12 months to 26 months

the mean follow-up was(15±2)months.Visual acuity

epithelial healing

corneal transparency

corneal neovascularization and transplanted amniotic membrane were observed.Results:After fresh amniotic membrane transplantation

ocular surface was soon stable

immune rejection and secondary infection didn’t occur.In 19 of 20 cases(23 eyes) the amniotic membrane autolyzed or disappeared with epithelized corneal surface at 14 to 28 days after operation.In one case(one eye) autolyzed corneal ulcer occurred at 12 days after operation.After another medication treatment was invalid

lamellar keratoplasty was performed.In other cases with AMT visual acuity keeps CF/5cm.Conclusion:Fresh amniotic membrane transplantation can lighten corneal inflammation in acute course of burn

can prevent ocular surface from ulcer and deliquescion

can fasten the stabilization and reduce corneal neovascularization

which provide a good basis for the following keratoplasty.With regard to severe eye burn

the effect of AMT is limited.