166例乳腺癌患者临床病理学特征及其与预后的关系

郭慧琳; 张幸平

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166例乳腺癌患者临床病理学特征及其与预后的关系

临床研究 | 更新时间：2024-01-17

- 166例乳腺癌患者临床病理学特征及其与预后的关系
- Clinicopathological features and their relationship with prognosis in 166 cases of breast cancer
- 重庆医科大学学报 2008年第4期页码：486-489
- 作者机构：
  
  1. 重庆医科大学附属第一医院肿瘤科
  2. 重庆医科大学附属第一医院肿瘤科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R737.9
- 纸质出版日期：2008，
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[1]郭慧琳,张幸平.166例乳腺癌患者临床病理学特征及其与预后的关系[J].重庆医科大学学报,2008(04):486-489+506.

GUO Hui-lin, et al. Clinicopathological features and their relationship with prognosis in 166 cases of breast cancer[J]. Journal of Chongqing Medical University, 2008,(4):486-489.
[1]郭慧琳,张幸平.166例乳腺癌患者临床病理学特征及其与预后的关系[J].重庆医科大学学报,2008(04):486-489+506. DOI：

GUO Hui-lin, et al. Clinicopathological features and their relationship with prognosis in 166 cases of breast cancer[J]. Journal of Chongqing Medical University, 2008,(4):486-489. DOI：

摘要

目的:分析166例乳腺癌患者临床病理学特征

筛选预后不良因素

以指导临床治疗。方法:回顾性分析166例原发性乳腺癌患者的临床资料

复习病理切片相关指标

分析患者临床病理学特征与预后的关系。结果:全组3年生存率为87.0%

5年生存率为77.0%;3年局部复发率为7.1%

3年远处转移率为21.0%。单因素分析显示肿瘤大小、腋窝淋巴结转移情况、ER、PR、绝经情况、组织学分级和临床分期对预后有影响;多因素Cox回归分析显示绝经情况、PR、淋巴结转移情况和组织学分级是独立预后因素。结论:绝经情况、激素受体、淋巴结转移情况和组织学分级是乳腺癌独立预后因素。

Abstract

Objective:To study the relationship between clinicopathological and biological characteristics and prognosis in 166 patients with breast cancer.Methods:The clinicopathological data of 166 patients with primary breast cancer were analyzed retrospectively.The histological specimens were reviewed.The expression of ER and PR was assessed by immunohistochemistry.Results:The 3-year overall survival rate and 5-year survival rate were 87.0% and 77.0%

respectively.The 3-year local recurrence rate was 7.1%

and the 3-year metastasis rate was 21.0%.The univariate analysis showed that the survival rate was related to the tumor size

lymph node involvement

menopause status

clinical stage and pathologic grade.The COX multivariate analysis identified that only menopause status

lymph node involvement and pathologic grade were significant independent prognostic factors.Conclusion:Our analysis demonstrates that menopause status

lymph node involvement and pathologic grade are significant independent prognostic factors.

关键词

乳腺肿瘤预后

Keywords

Breast cancerprognosis

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