Objective:To assess the health risk of the chemical pollutants in drinking water for humans to present the basis for interrelated department in making the related water quality standard.Methods:A USEPA health risk assessment model was used to assess health risk associated with concentrations of chemical pollutants in drinking water after investigating concentrations of As、Hg、Cr6+、Pb、Cd and Cu in drinking warter in 37 counties of M city based on 43 random samples

according to the practical data of drinking water resources.Results:(1)The health risk comparisons caused by gene toxic substances was Cr6+>As>Cd

and risk comparisons caused by body toxic substances was Pb>Cu>Hg.The health risk of gene toxic substances was more distinct than that body toxic substances.(2)The total health risk of all pollutants in drinking water was 7.18×10-5a-1 in 2003

2.12×10-4a-1 in 2004 and 2.28×10-4a-1 in 2005

all of which exceeded 5.0×10-5a-1

the value recommended by ICRP

and greatly exceeded the standards recommended by the Sweden Bureau of 2 Environment Protection and the Holland Ministry of Building and Environment Protection.Conclusions:There is reference value in our research for risk management of drinking water resources and water enviroment poretcting measures.