ZHOU Qin, et al. Expression of PTEN in endometrial carcinoma and its clinical significance[J]. Journal of Chongqing Medical University, 2008,(2):186-188.
ZHOU Qin, et al. Expression of PTEN in endometrial carcinoma and its clinical significance[J]. Journal of Chongqing Medical University, 2008,(2):186-188.DOI:
Objectives:To study the expression of PTEN in endometrial carcinoma under different pathological factors and to discuss its relationshipwith the occurrence of endometrial carcinoma and the clinical significance.Methods:The expressions of PTEN in 40 cases of endometrial carcinoma
10 cases of atypical hyperplasia and 10 cases of normal endometria were examined by immunohistochemical method.Result:The positive staining rate of PTEN in endometrial carcinoma was 55.00%
and that in normal endometria was 100.00%.There was no obvious correlation between the expression of PTEN in endometrial carcinoma and different pathological factors such as clinical staging
depth of myometrial invasion and lymph node metastasis.Conclusion:The expression lack of PTEN exists in endometrial carcinoma
and PTEN has an important role in the occurrence of endometrial carcinoma.