WU Li-xian, et al. Establishment of rabbit endocarditis models caused by enterococcus[J]. Journal of Chongqing Medical University, 2008,(4):437-440.DOI:
objective:To establish Rabbit endocarditis models caused by Enterococcus faecalis for studying virulence of Enterococcus.Methods:Standard strain OG1RF and sprE gene deficient mutant of Enterococcus faecalis were used to establish Rabbit endocarditis models.The index of endocarditis was detected to show virulence change.Results:The size
weight and Colony count of vegetation of sprE mutant groups were smaller than those of wild-type OG1RF groups in a rabbit endocarditis model.Conclusion:The Rabbit endocarditis models caused by Enterococcus were establised successfully
which would be used to study other virulence factor of Enterococcus faecalis.