Objective:To explore the optimal way of oxygen nebulization that can effectively induce sputum and prevent post-operative pulmonary complications for patients underwent esophagectomy. Methods: 24h Continuous oxygen nebulization(0.45% sodium chloride as regular automized liquid) was administered in 60 patients after esophagectomy in the Department of Cardiothoracic Surgical

the First Affiliated Hospital

Chongqing Medical University. Results: No statistics difference of the blood-gas test were found between the tow groups(P>0.05).Among the test group.the number of medium nebulization were significatly more than that in the contrast group(P<0.01).while the number of patient lack of nebulization were significatly less than the contrast group(P<0.01).And the over nebulization patients were no significate difference between two groups(P>0.05).Conclusions: Early continuous and administration of oxygen nebulization with 0.45%sodium chloridecan not only decrease the Visco-elasticity of sputum

but aslo sustain the stability of oxygen partial pressure in blood in the study.