SHI Xiu-quan, LIU Dan, LIU Jun. Comparison of variance of weights in meta-analysis models and its correlation with I-square[J]. Journal of Chongqing Medical University, 2011,36(11):1350-1352.
SHI Xiu-quan, LIU Dan, LIU Jun. Comparison of variance of weights in meta-analysis models and its correlation with I-square[J]. Journal of Chongqing Medical University, 2011,36(11):1350-1352.DOI:
Objective:To explore the difference in variance of weights(s2w) between two models and its correlation with I-square of heterogeneity(I2) in meta-analyses.Methods:Weights and I2 were extracted from meta-analyses which were published in recent three years
then s2w were computed.The difference in s2w was compared between two models and the correlation was investigated between s2w s2w and I2.Results:s2w in random-effect model was lower than that in fixed-effect model(t=2.739
P=0.015);and the correlation coefficient between s2w and I2 was-0.505 and P-value was 0.039.Conclusion:s2w in random-effect model is significantly lower than fixed-effect model and a negative correlation between s2w and I2 exists.It is important to understand how to assign weight in two models
even in the study and suitable explanation of the results in meta-analyses if the reasons of s2w difference and correlation between I2 and s2w are thoroughly searched.