Objective：To demonstrate the feasibility and safety of sutureless retroperitoneoscopic partial nephrectomy with bipolar co－agulation. Methods：From December 2012 to June 2016，523 patients underwent retroperitoneoscopic partial nephrectomy（RPN） at our institution were enrolled. Excluding tumor staging greater than T1a，suture or transperitoneal laparoscopic cases，there were 75 cases of sutureless RPN. Results：The average RENAL score was 4.5；the average age of patients was 53.4 years old； the body mass index was 24.1 kg/m2；the average tumor diameter was 1.9 cm；the average warm ischemia time was 6.9min；the average blood loss was 88.8 mL；blood transfusion was needed in one case；no transit was open；the complication rate was 9.3%；the average time of ischemia was 6.9min；the average postoperative hospital stay was 6.4 days；the mean creatinine was 71.5 mmol/L before operation；the average creatinine was 76.5 mmol/L after operation and the average follow-up time was 32.1 months. Conclusion：Sutureless RPN is a safe and feasible and oncological effective method. Given that it is free from laparoscopic knotting and stitching，it may encourage laparo－scopic novice to learn confidently and master this more difficult procedure.