Objective To explore the clinical application effect and safety of gastrointestinal endoscopic high frequency electrotomy(HFE) combined with argon plasma coagulation(APC) in the treatment of upper gastrointestinal polyps.Methods A total of 98 patients with upper gastrointestinal polyps in our hospital from January 2016 to January 2017 were divided into control group and observation group according to surgical menthods

46 cases in the control group were treated with HFE combined with microwave coagulation(MC) under gastrointestinal endoscopy

52 cases in the observation group were treated with HFE combined with APC under gastrointestinal endoscopy.The operation time

NRS score of postoperative pain

success rate of first surgery and incidence of complications between the two groups were compared. Results The operation time and NRS scores of the patients with pedunculated polyp

flat polyp and sessile colorectal polyp in the observation group were less than those in the control group(P<0.05).The success rate of first surgery in the observation group was higher than that in the control group(P<0.05).The incidence of complications in the observation group were lower than that in the control group

the difference was significant(P<0.05). Conclusion HFE combined with APC under gastrointestinal endoscopy is a feasible operation for patients of upper gastrointestinal polyps with high safety.