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1. 首都医科大学附属北京友谊医院平谷医院心胸综合外科
2. 北京儿童医院胸外科
纸质出版日期:2019,
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葛广林, 李宏芹, 彭小乐, 等. 青少年原发性自发性气胸患者胸腔镜术后复发的危险因素分析[J]. 局解手术学杂志, 2019,(5):387.
GE Guanglin, LI Hongqin, PENG Xiaole, et al. Risk factors of recurrence after adolescent spontaneous pneumothorax thoracicassisted surgery[J]. null, 2019,(5):387.
目的 分析青少年原发性自发性气胸(PSP)患者胸腔镜术后复发的危险因素,为PSP术后预防复发提供依据。方法纳入对象为2010年11月至2016年1月北京友谊医院平谷医院胸外科收治的236例PSP患者,随访24个月,记录术后复发情况。将复发患者设为观察组,未复发患者设为对照组,收集所有患者病历资料,探讨性别、年龄、住院时间等对PSP复发的影响,并通过单因素与logistic回归分析探讨PSP患者胸腔镜术后复发的独立危险因素。结果 236例患者术后24个月内复发28例,复发率11.86%,左侧16例,右侧12例,复发时间为(8.56±2.12)个月,复发年龄(24.34±3.54)岁。2组患者身体质量指数(BMI)、胸膜固定术、性别、术后吸烟、术前PSP发作次数、术后漏气时间、胸管维持时间对患者术后复发的影响差异具有统计学意义(P<0.05);而年龄、发病部位、住院时间、手术时间、胸膜固定方法对患者术后复发的影响差异无统计学意义(P>0.05)。多因素logistic回归分析结果显示术前PSP发作次数大于等于3次(OR=2.543,95%CI:0.765~6.646)、术后吸烟(OR=2.764,95%CI:1.032~7.521)、BMI<18.5 kg/m2(OR=2.214,95%CI:1.211~9.623)、未进行胸膜固定术(OR=2.486,95%CI:1.186~7.326)是PSP患者胸腔镜术后复发的独立危险因素。结论 PSP发作次数大于等于3次、术后吸烟、BMI<18.5 kg/m2、未进行胸膜固定术均会增加PSP患者胸腔镜术后复发风险。
Objective To investigate the risk factors of recurrence after adolescent pimary spontaneous pneumothorax(PSP) thoracicassisted surgery
and to provide a theoretical basis for the prevention of the PSP recurrence. Methods A total of 236 patients with PSP admitted into thoracic surgery department of Pinggu hospital of Beijing friendship hospital from November 2010 to January 2016 were selected.All patients were followed up for 24 months
the recurrence rate was recorded.Recurrence patients were included into observation group
nonrelapse patients were enrolled into the control group.All patients′ medical records were collected to study the influence of gender
age
length of stay on the recurrence of PSP.Then the independent risk factors for PSP recurrence after thoracoscopic surgery were analyzed by single factor and logistic regression analysis. Results During the followup of 24 months
the recurrence rate was 11.86% (28 cases) among 236 patients
with 16 cases on the left side and 12 cases on the right side;the recurrence time was (8.56±2.12) months
and the mean age was (24.34±3.54) years old.Body mass index (BMI)
pleurodesis
gender
postoperative smoking
number of preoperative PSP episodes
postoperative leak time
and thoracic tube drainage time were significantly different between two groups(P<0.05)
while no difference was found in the age
incidence site
length of stay
operation time
pleura fixation between two groups (P>0.05).Multivariate logistic regression analysis showed that preoperative PSP episodes ≥3 times(OR=2.543
95%CI:0.765~6.646)
postoperative smoking(OR=2.764
95%CI:1.032~7.521)
BMI<18.5 kg/m2(OR=2.214
95%CI:1.211~9.623)
without pleurodesis(OR=2.486
95%CI:1.186~7.326)were independent risk factors for PSP recurrence after thoracoscopic surgery. Conclusion PSP episodes ≥3 times
postoperative smoking
BMI<18.5 kg/m2
without pleurodesis may increase the risk of PSP recurrence after thoracoscopic surgery.
青少年原发性自发性气胸胸腔镜术复发危险因素
adolescentpimary spontaneous pneumothoraxthoracoscopic surgeryrecurrencerisk factors
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