Objective To investigate the influencing factors of pregnancy failure in patients with threatened abortion to provide a theoretical basis for the formulation of clinical strategies. Methods A total of 200 patients with threatened abortion admitted to our hospital from March 2018 to March 2020 were selected as the study subjects and assigned to groups following their delivery status. Influencing factors of pregnancy failure in patients with threatened abortion were analyzed using Logistic regression. Results There were 135 patients in the good pregnancy group and 65 patients in the poor pregnancy group. Univariate analysis showed that there were significant differences in pregnancy outcomes among study subjects of different ages as well as previous history of spontaneous abortion

early vaginal bleeding

massive vaginal bleeding

vaginitis

genital tract mycoplasma/chlamydia infection

uterine malformations

uterine fibroids

luteal phase dysfunction

large intrauterine hematoma and hypothyroidism during pregnancy（all P<0.05）. Logistic regression analysis showed that age ≥ 35 years old

previous history of spontaneous abortion

massive vaginal bleeding

vaginitis

genital tract mycoplasma/chlamydia infection

uterine malformation

uterine fibroids

luteal phase dysfunction and large intrauterine hematoma were all risk factors for pregnancy failure in patients with threatened abortion（all P<0.05）. Conclusion A host of risk factors affecting pregnancy failure remain in patients with threatened abortion. It is necessary to take certain preventive measures for patients with threatened abortion combined with risk factors to reduce the pregnancy failure rate in clinical practice.