Objective To investigate the effects of intensive Tri-Ball respiratory muscle exercise combined with continuous oxygen therapy treatment on respiratory and motor functions in patients with chronic obstructive pulmonary disease（COPD） in stable phase. Methods A total of 132 patients with stable COPD admitted to a hospital in Nanyang from May 2018 to May 2020 were selected as subjects

who were assigned to an observation group and a control group using the random number table method

with 66 cases in each group. Patients in the control group received continuous oxygen and drug therapies

and patients in the observation group received Tri-Ball respiratory muscle exercise in addition to the therapies in the control group

and patients in both groups were treated continuously for 3 months. Respiratory function [arterial partial pressure of oxygen（PaO

2

）

arterial partial pressure of oxygen saturation（SaO

2

）

arterial partial pressure of carbon dioxide（PaCO

2

）]

motor function [6-minute walk test（6MWT）

maximum oxygen uptake(VO

2max

)

anaerobic threshold（AT）]

clinical symptoms [COPD Assessment Test（CAT） scores

modified Medical Research Council scale（mMRC）]

were compared between the two groups before treatment and at 3 months of treatment. Results The PaO

2

SaO

2

6MWT

VO

2max

and AT levels after treatment were higher in both groups than those before treatment

with the observation group higher than the control group

and the differences were statistically significant（P

<

0.05）. PaCO

2

levels after treatment were lower in both groups than those before treatment

with the observation group lower than the control group

and the differences were statistically significant（P

<

0.05）. CAT and mMRC scores of patients in both groups were lower than those before treatment

with the observation group lower than the control group

and the differences were statistically significant（P

<

0.05）. Conclusion Intensive Tri-Ball respiratory muscle exercise in combination with continuous oxygen therapy can improve respiratory function and motor function and relieve clinical symptoms in patients with COPD in stable phase. These advantages justify a wider application of this therapy clinically.